from cffi import FFI
ffibuilder = FFI()

ffibuilder.set_source("selfsample",
    r"""
        #include <alsa/asoundlib.h>
        #include <math.h>
        #include <errno.h>
        #include <unistd.h>

        snd_pcm_t *out_handle;
        snd_pcm_t *in_handle;

        snd_pcm_stream_t out_stream = SND_PCM_STREAM_PLAYBACK;
        snd_pcm_stream_t in_stream = SND_PCM_STREAM_CAPTURE;

        snd_pcm_hw_params_t *out_params;
        snd_pcm_hw_params_t *in_params;

        char *pcm_out_name;
        char *pcm_in_name;

        #define PERIOD_SIZE 8192
        #define SAMPLE_RATE 48000

        snd_pcm_t *open_output_stream();
    """,
    libraries=[])

ffibuilder.cdef(r"""
        typedef int... snd_pcm_uframes_t;

        struct snd_pcm_t *
        open_output_stream()
        {
            int rate = 48000;       /* Sample rate */
            int exact_rate;         /* Sample rate returned by */
                                    /* snd_pcm_hw_params_set_rate_near */
            int dir;                /* exact_rate == rate --> dir = 0 */
                                    /* exact_rate < rate  --> dir = -1 */
                                    /* exact_rate > rate  --> dir = 1 */
            int periods = 2;        /* Number of periods */
            snd_pcm_uframes_t periodsize = PERIOD_SIZE; /* Periodsize (bytes) */
            snd_pcm_t *handle;

            if (snd_pcm_open(&handle, pcm_out_name, out_stream, SND_PCM_NONBLOCK) < 0) {
                fprintf(stderr, "Error opening PCM device %s\n", pcm_out_name);
                return(NULL);
            }

            if (snd_pcm_set_params(handle,
                                   SND_PCM_FORMAT_S16_LE,
                                   SND_PCM_ACCESS_RW_INTERLEAVED,
                                   1,
                                   48000,
                                   1,
                                   50000) < 0) {   /* 0.5sec */
                return(NULL);
            }

            return handle;
        }
    """)

Traceback (most recent call last):
  File "selfsample_build.py", line 86, in <module>
    """)
  File "/usr/lib64/python3.6/site-packages/cffi/api.py", line 106, in cdef
    self._cdef(csource, override=override, packed=packed)
  File "/usr/lib64/python3.6/site-packages/cffi/api.py", line 120, in _cdef
    self._parser.parse(csource, override=override, **options)
  File "/usr/lib64/python3.6/site-packages/cffi/cparser.py", line 308, in parse
    self._internal_parse(csource)
  File "/usr/lib64/python3.6/site-packages/cffi/cparser.py", line 351, in _internal_parse
    raise CDefError("unrecognized construct", decl)
cffi.error.CDefError: line 5: unrecognized construct